Prolotherapy Research
Y. King Liu, M.D.
In 1983, Y. King Liu performed a study using the knee ligament in rabbits.
(Liu, Y. et al. An in situ study of the influence of a sclerosing solution
in rabbit medial collateral ligaments and its junction strength. Connective
Tissue Research, 1983; 11:95-102.) This study was done to confirm Dr.
Hackett's earlier work and better quantify the strength of the tissue formed
by Prolotherapy. In this study, a
five percent
sodium morrhuate solution, an extract of cod liver oil, was
injected into the femoral and tibial attachments of the medial collateral
ligament, the inside knee ligament.
The ligaments were injected five times and then compared to noninjected
ligaments. The results showed that in every case Prolotherapy significantly
increased ligamentous mass, thickness, and cross-sectional area as well as
the ligament strength. In a six-week period, ligament mass increased by 44
percent, ligament thickness by 27 percent, and the ligament-bone junction
strength by 28 percent. This research was yet another attestation to the
effectiveness of Prolotherapy
Prolotherapy
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